Abstract The paper reassesses a survival at tumor recurrence in soft matter. First, the stability of structural motifs under shear in clusters of dipolar spheres is cha racterized. Next, there are introduced transitions between polymer knots and rhythms of these transitions are obtained. The sensor is built for these rhythms. Treatment, with a tensile force protocol, is modeled, when the tumor in soft matter is observed by the above sensor. Survival probability, at tumor recurrence in soft matter, is defined for the treatment with a tensile force protocol .It is stated that the survival probability at a tensile force protocol treatment in soft matter confirms or specifies the prognostic survival of 32 patients with breast cancer.